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Writer's picturePriyanka Thirumurti

Neuroscience of Music

Updated: Nov 3



The Development of the Brain and Music through Co-Evolution


The evolution of the human brain and the role of music in society are both incredibly complex and intertwined. Research suggests that music predates language in our evolutionary history, as early humans were likely more emotionally expressive through music than they were able to communicate with words. One fascinating example of this is “motherese” or child-directed speech, which incorporates a musical quality to engage infants.


Humans possess a remarkable ability to process auditory information, surpassing that of great apes. This enhanced auditory skill is linked to an increase in the size of the dorsal area of the temporal lobe, which is crucial for receiving and interpreting speech. Rhythm plays a vital role in how our brains process music, with studies showing that the right hemisphere is primarily responsible for recognizing fundamental musical elements such as tone, timbre, pitch, harmony, and rhythm. However, these musical components are not limited to the right side of the brain; both hemispheres contribute to our musical understanding.


Interestingly, there is a connection between musical creativity and certain neuropsychiatric disorders, like bipolar disorder, although this occurs in a small percentage of the population. Additionally, music therapy has emerged as a promising therapeutic option for various brain disorders and neuropsychiatric illnesses, highlighting music’s profound impact on our mental health and cognitive function.



How Music Enhances Memory and Triggers Recall

Research has shown that music can significantly boost certain types of memory. In one study involving mice, scientists discovered that listening to music enhanced memory performance as measured by a passive avoidance test. This process also influenced the production of brain-derived neurotrophic factor (BDNF), a protein vital for learning and memory, in the hippocampus of these animals. Mice exposed to music for 21 days exhibited increased levels of BDNF specifically in the hippocampus, while no changes were found in other brain regions like the striatum or frontal cortex. Remarkably, these musically exposed mice demonstrated better behavioral responses in the memory test, marking the first evidence that music can influence BDNF production in the adult mouse hippocampus.


But music does more than just enhance memory; it can also evoke powerful memories and heighten our sensory experiences. Researchers have explored how different brain regions respond to music, particularly focusing on individuals with varying levels of musical training. Musicians, for example, tend to process musical tones more efficiently than non-musicians. They possess superior auditory memory for sounds and are more sensitive to acoustic features. Interestingly, this enhanced ability may be linked to mirror neurons, which are known to activate when we observe or engage in actions, influencing our emotional responses.


Additionally, there’s substantial evidence that musical training promotes changes in the brain’s structure, known as neuroplasticity. Studies have shown that musicians often have different gray matter distributions in specific brain areas compared to non-musicians. This suggests that engaging with music not only enriches our memory and recall but also physically reshapes our brains.



The Relationship Between Music and Prosocial Behavior

Music not only enriches our lives but also influences our social behaviors at a biological level. One fascinating connection is between music and the hormone oxytocin, often referred to as the “love hormone,” which plays a key role in fostering prosocial behavior—the actions that benefit others. Research shows that after a singing lesson, adults experience a noticeable increase in their salivary oxytocin levels.


In another study focusing on sensory experiences, participants who listened to slow, relaxing music had elevated oxytocin levels and a lower heart rate, suggesting a calming effect that promotes social bonding. In contrast, fast-paced music didn’t significantly impact oxytocin but was found to lower cortisol levels, a stress hormone, while increasing overall arousal. These findings highlight how different types of music can affect our mood and social interactions, reinforcing the powerful connection between music and our emotional well-being.


Perception of Music in Understanding the Neuroscience of Music

When exploring the fascinating world of music neuroscience, it’s crucial to grasp how we perceive music, the therapeutic potential it holds, and the clinical studies examining its effects. Our experience of music unfolds in three distinct stages. First, we encounter the basic sounds—this is where we recognize the auditory stimuli. Next, we dive deeper into the structural elements of the music, analyzing it at both a basic level (such as pitch, intensity, rhythm, duration, and timbre) and a more advanced level (like phrasing, timing, and themes). Finally, we arrive at the third stage: identifying the piece being played.


The therapeutic power of music lies in its ability to communicate in ways that words often cannot. Music creates a bridge between our conscious selves and the parts of us that we may not yet understand. This unique connection is what gives sound its profound healing potential, opening nonverbal channels of communication and allowing us to explore our emotions and experiences more deeply.




Music's Effect on the Brain

Research into music’s impact on the brain has revealed some fascinating insights, particularly through what’s known as the Mozart effect. This phenomenon suggests that listening to Mozart’s piano sonata K448 can enhance brain function. But the questions don’t stop there—scientists are exploring whether the emotions stirred by music might be linked to higher cognitive abilities simply through listening.


Advanced imaging techniques like positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) have shown that listening to music we enjoy activates both cortical and subcortical areas of the brain responsible for processing emotions. Conversely, dissonant or unpleasant chords can trigger activity in the amygdala, a region associated with emotional responses. Moreover, studies indicate that listening to music can lower cortisol levels, which helps reduce stress and improve mood. So, not only does music make us feel good, but it also has measurable effects on our brain and emotional well-being.


The Stress-Relieving Benefits of Music

Music has remarkable powers to alleviate stress, making it a valuable addition to medical treatments with proven clinical benefits. Numerous studies have shown that stress can disrupt the immune system, leading to changes in both humoral and cellular immune responses, which in turn can increase health risks. One of the pioneering studies in this area, conducted by Bittman and colleagues, demonstrated that group drumming significantly boosted natural killer cell activity, lymphokine-activated killer cell activity, and improved the ratio of dehydroepiandrosterone to cortisol in healthy individuals.


Current research indicates that while the evidence is still evolving, there is moderate support for the idea that listening to familiar and enjoyable music—a key component of music therapy—can reduce disease burden and enhance overall well-being. This effect has been particularly noted in patients dealing with conditions such as cardiovascular disease, cancer pain, epilepsy, depression, and dementia. By harnessing the soothing power of music, we can help patients find relief from tension and improve their quality of life.


The Neurobiological Role of Music in Social Bonding

Music plays a fascinating role in fostering social connections among individuals. Researchers argue that music, along with dance, has co-evolved both biologically and culturally to serve as a powerful tool for social bonding. Trust is foundational to all human interactions, and music is believed to help cultivate this trust. While the specific neural mechanisms behind this phenomenon are still being explored, one thing is clear: music can evoke and regulate a wide range of emotions, triggering the release of neurohormones in the brain. Essentially, music and dance have evolved together, intertwining brain chemistry with cultural behaviors to create a unique form of expression. This interplay has given rise to methods for inducing altered states of consciousness, enriching our social experiences and deepening our connections with one another.



Sources

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  3. Molnar-Szakacs, Istvan and Overy, Katie. Music and mirror neurons: from motion to 'e'motion. SCAN (2006) 1, 235-241.

  4. Harvey, Alan. Links Between the Neurobiology of Oxytocin and Human Musicality. Frontiers in Human Neuroscience. 14: 1-19. 2020.

  5. Boso, Marianna et al. Neurophysiology and neurobiology of the musical experience. Functional Neurology; 21(4): 187-191. 2006.

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  7. Zatorre, Robert. Music, the food of neuroscience? Nature; 434: 312-315. 2005.

  8. Freeman, Walter J. A neurobiological role of music in social bonding. University of California. 2000.




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